PVT1 Cancer


PVT1 Cancer

Cancer is currently the second most common cause of death worldwide and it is projected to become the most common cause of death in the near future based on current trends. Human chromosome 8q24 is a well-established region of genomic instability and cancer susceptibility. While poor in protein-coding genes, it is rich in non-coding genes. One non-protein coding gene located downstream of MYC at chromosome 8q24 is PVT1. The PVT1 non-protein coding gene has been implicated in very many cancers, including cervical cancer, bladder cancer, colorectal cancer, gastric cancer, hepatocellular carcinoma, lung cancer, breast cancer, ovarian cancer, acute myeloid leukemia and Hodgkin’s lymphoma. It encodes six annotated microRNAs (miR-1204, miR-1205, miR-1206, miR-1207-3p, miR-1207-5-p, and miR-1208), some of which are also being implicated in carcinogenesis. Thus, PVT1 is emerging as a major player in cancer. This article collection will compile in one location the most recent and up to date information on the emerging role of PVT1 in various cancers..

How we work:

After submission, an acknowledgement with manuscript number is sent to the corresponding author within 7 working days. A 21 day window time frame is allotted for peer-review process wherein multiple experts are contacted. Author proof is generated within 7 working days after the acceptance decision.

Benefits on Publication:

Open Access: Permanent free access to your article upon publication ensures extensive global reach and readership.

Easy Article Sharing: Our open access enables you to share your article directly with colleagues through email and on social media via a single link, permitting third party reuse with appropriate citation in addition to the retention of content copyright by the author.

Global Marketing: Through promotion in a targeted global email announcement or press release, your article will be seen by thousands of the top-most thought-leaders in your field.

Social Media Exposure: Extended reach for your article through links on Twitter accounts provides maximum visibility worldwide.

Reprints: Distribute your work to colleagues and at conferences as we provide hard copy color reprints of your article on order.

Media Contact:
Marcy A
Journal Manager
Journal of Medical and surgical pathology
Email: surgpathology@emedsci.com