Cerebellar Ataxia in HIV Patient


Acute cerebellar ataxia (ACA) is a disorder that occurs when the cerebellum becomes inflamed or damaged. The cerebellum is the area of the brain responsible for controlling gait and muscle coordination. The term ataxia refers to a lack of fine control of voluntary movements. Here we present a case report of a rare presentation of efavirenz associated cerebellar ataxia in a patient of HIV/AIDS.

Ataxia in a patient of HIV is generally secondary to an infectious, vascular or neoplastic cause. Most infections are opportunistic and unlikely to occur when CD4 levels are adequate. Focal lesions resulting from opportunistic infections such as toxoplasmosis and progressive multifocal leukoencephalopathy or primary CNS lymphoma were excluded as MRI brain was normal. Other metabolic causes were excluded with relevant investigations. Absence of fever and prodormal symptoms makes diagnosis of cerebellitis or brainstem encephalitis unlikely 

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Robert Har
Associate Editor
Journal of Antivirals & Antiretrovirals